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Long Acting Neuroleptic Drugs

Long Acting Neuroleptic Drugs The term "long-acting neuroleptic" is used to describe a member of a group of tranquilizers that has been used in wildlife over the past 20 years. Tranquilizers comprise one of many groups of pharmacologically active agents that have their primary effect by modulating neurotransmitter activity within the central nervous system. There are five main neurotransmitters that are involved in behavior modification: acetylcholine, dopamine, norepinephrine, serotonin, and γ -aminobutyric acid (GABA). Tranquilizers, also referred to as neuroleptics, act as antipsychotics through their action as dopamine antagonists. Tranquilizers The antipsychotic action of dopamine antagonists is achieved by blocking dopamine receptors and increasing turnover of dopamine in the limbic system of the brain, producing a state of "ataraxia" or behavioral quieting that is characterized by decreased emotional reactivity and aggression, and relative indiffe...