KNOW ABOUT ONE DRUG EVERY DAY XYLAZINE
KNOW ABOUT ONE DRUG EVERY DAY XYLAZINE Type Alpha 2 -adrenergic agonist structurally related to clonidine. Alternative Names Xylazine hydrochloride. Pharmacology & General Information Pharmacology Potent alpha 2 -adrenergic agonist (alpha 2 -adrenoceptor stimulant). CNS effects: Causes sedation and CNS depression. Muscle relaxation is mediated through central nervous system pathways. Emesis (in cats and sometimes in dogs, but not occurring in horses, cattle sheep, goats) is thought to be centrally mediated. Depresses thermoregulatory mechanisms. Cardiovascular effects: Initial increased total peripheral resistance and increased blood pressure. Longer period of lowered (below baseline) blood pressure. Bradycardia. Due to sino-atrial and atrioventricular heart block, partially in response to the initial hypertension. Second degree heart block or other arrhythm...