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Pharmacokinetics (Pk) - Routes of administration of drugs

Pharmacokinetics Pharmacokinetics is the quantitative study of drug movement in, through and out of the body. Pharmacokinetics deals with the movement of drugs. A drug that is administered must be absorbed, distributed, metabolized and excreted. Pharmacokinetics deals with absorption, distribution, metabolism and excretion of drugs. In simple words it is described as what the body does to the drug. The intensity of response is related to concentration of the drug at the site of action, which in turn is dependent on its pharmacokinetic properties. Pharmacokinetic considerations, therefore, determine the route of administration, dose, latency of onset, time of peak action, duration of action and frequency of administration. Pharmacokinetic information is helpful in determining and adjusting the drug dosage schedules and in interpreting drug concentration data. A drug that is administered must move through different parts of the body and for this movement it must pass through vari...

Pharmacological terms

Pharmacological terms used for drugs acting on various systems 1. Drugs acting on mouth and salivary glands a. Sialogogues / Sialics : These are drugs which increase the secretion of saliva. They may act either directly upon the gland or their secreting nerves or may act reflexly. i.                     Direct sialogogues : Eg. Pilocarpine, Physostigmine. ii.                  Reflexly acting sialogogues : Eg. Alcohol, Acids, Bitters and Aromatics. Through sensory nerve ending in the mouth or through the stomach. Eg. Ipecacuanha, Antimony. b. Antisialics : are drugs which diminish the secretion of saliva. i.                     By paralysing secretary nerve endings. Eg. Atropine ii.   ...